Synthesis and Characterizations of Dipeptide Derivative of Gentamicin
Abstract The target derivative are gentamicin linked with L-Val- L-Ala by an ester linkage.These were synthesized by esterification method, which included the reaction of -OH hydroxyl group on (carbon No.5) of gentamicin with the acid chloride of the corresponding dipeptide, The preparation of new derivative of gentamicin involved protected the pri